Synthesis of essential drugs


Книга Synthesis of essential drugs

Автор: R.S. Vardanyan; Victor J. Hruby
Название: Synthesis of essential drugs
Язык: English
Издательство: Amsterdam; Boston: Elsevier
Год: 2006
Формат: pdf
Размер: 15 mb
Страниц: 634

This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis.
The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists.
Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis.
Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHO’s "Essential List of Drugs."
For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.
This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs.
 Table of contents:
Preface, Pages vii-viii
1. General Anesthetics, Pages 1-8
2. Local Anesthetics, Pages 9-18
3. Analgesics, Pages 19-55
4.Soporific Agents (Hypnotics and Sedative Drugs), Pages 57-68
5. Anxiolytics (Tranquilizers), Pages 69-82
6. Antipsychotics (Neuroleptics), Pages 83-101
7. Antidepressants, Pages 103-116
8. Central Nervous System Stimulants, Pages 117-124
9. Antiepileptic Drugs, Pages 125-133
10. Antiparkinsonian Drugs, Pages 135-141
11. Adrenergic (Sympathomimetic) Drugs, Pages 143-159
12. Adrenoblocking Drugs, Pages 161-177
13. Cholinomimetics, Pages 179-193
14. Anticholinergic Drugs, Pages 195-208
15. Muscle Relaxants, Pages 209-218
16. Antihistamine Drugs, Pages 219-235
17. Cardiotonic Drugs, Pages 237-243
18. Antiarrhythmic Drugs, Pages 245-255
19. Antianginal Drugs, Pages 257-267
20. Hypolipidemic Agents, Pages 269-276
21. Diuretics, Pages 277-293
22. Antihypertensive Drugs, Pages 295-310
23. Drugs for Treating Respiratory System Illnesses, Pages 311-321
24. Anticoagulants, Antiaggregants. Thrombolytics, and Hemostatics, Pages 323-335
25. Thyroid Hormone and Antithyroid Drugs, Pages 337-342 26.lnsulin and Synthetic Hypoglycemic Agents, Pages 343-348
27. Corticosteroids, Pages 349-363
28. Female Sex Homiones, Pages 365-379
29. Male Sex Hormones and Anabolic Steroids, Pages 381-387
30. Antineoplastics, Pages 389-418 31.lmmunopharmacological Drugs, Pages 419-424
32. Antibiotics, Pages 425-498
33. Antimicrobial Drugs, Pages 499-523
34. Antimycobacterial Drugs, Pages 525-534
35. Antifungal Drugs, Pages 535-547
36. Anti viral Drugs, Pages 549-557
37. Drugs for Treating Protozoan Infections, Pages 559-582
38. Antihelmintic Drugs, Pages 583-593
Index, Pages 595-617
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